1. Abstract
2. Composition of the Team
3. Research projects
4. Grants
1. Abstract
The immune system is a complex biological system. Its study must take into account 3 levels of organization: organism, cells and molecules, in their space-time dimension and so to benefit from the approaches in biology of the complex systems, in particular of those of the systems immunology.
The objectives :
- Integrate & model experimental data linked to differentiation, diversity and dynamics of immune system and T cells in particular, at multi-system levels (organism, cell, molecule, time, space)
- Obtain a global analysis of the immune system behavior and T cell differentiation under physiological and pathological situations
- Develop bioinformatics & biostatistics tools and multidisciplinary interactions in the field of complex systems
Focus on T cells in physiology/physiopathologies
- Modeling T-cell differentiation & dynamics
- Global analysis of T cells : Gene expression & Immune repertoires
- Pharmacogenomics of T cells
2. Composition of the team
Researchers
- Véronique Thomas-Vaslin, CR1 CNRS (I2D3 team leader)
- Adrien Six, PU UPMC (I2D3 team leader)
- Gilbert Bensimon, MCU-PH UPMC
- Pierre-André Cazenave, PU UPMC
- David Klatzmann, PU-PH UPMC (director I3)
- Alaa Abi-Haidar, postdoctoral fellow UPMC
Research assistants
- Wahiba Chaara, bioinformatics [contract UPMC, AP-HP]
- Nicolas Dérian, bioinformatics [contract UPMC, AP-HP]
- Hugues Ripoche, bioinformatics [CNRS]
Trainees
- Hang-Phuong Pham, Ph.D. biostatistics, UPMC, 2009-2012
- Julien Vibert, M2 M.Sc. BMC, UMPC ENS-Paris, 2012
Visiting Scientist
- Prof. Hugues Bersini, Université Libre de Bruxelles (invited Professor UPMC, Nov-Dec 2010)
- Chris McEwan, postdoctoral fellow
Former trainees
- Claire Lhuillier, M1 M.Sc. immunology, UPMC, 2011
- Benjamin Zerath, M1 M.Sc. bioinformatics, Univ. Evry Val d'Essonne, 2010
- Cira Dansokho, M1 & M2 M.Sc., immunology, UPMC, 2010-2011
- Sébastien Le Mentec, M2 M.Sc. bioinformatics, Univ. Diderot (Paris VII), 2009
- Camille Baey, M1 M.Sc. immunology, UPMC, 2009
- Natalia Korneychuk, M1 M.Sc., immunology, UPMC, 2009
- Fei Xu, M1 M.Sc., immunology, UPMC, 2009
- Emilie Franck, M2 M.Sc., immunology, UPMC, 2008
- Rachid Kerdous, M1 M.Sc., immunology, UPMC, 2008
- Anna Tchassovskikh, M2 M.Sc., immunology, UPMC, 2008
Funding
- UPMC
- CNRS
- Emergence UPMC
- Vieillissement CNRS
- Clinigene FP6
- Compuvac FP6 (terminated)
- DIM-Problématiques transversales aux systèmes complexes. ISC-PIF
Ecole doctorale
- Complexité du Vivant, UPMC